Tag: Bladder

Hypermethylation of E-cadherin, p16, p14, and RASSF1A genes in pathologically normal urothelium predict bladder recurrence of bladder cancer after transurethral resection.

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CONCLUSIONS: p14 hypermethylation could be involved in early stage of bladder carcinogenesis, and p14 hypermethylation in pathologically normal urothelium samples should be considered a predictor of bladder cancer recurrence.
PMID: 20800513 [PubMed - as supplied by publisher] (Source: Urologic Oncology) Source: MedWorm: Bladder Cancer

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Long‐term follow‐up of T1 high‐grade bladder cancer after intravesical bacille Calmette‐Guérin treatment

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Study Type – Therapy (cohort)
Level of Evidence 2b (Source: BJU International)

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Source: MedWorm: Bladder Cancer

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Commentary on “Prospective randomized controlled trial of robotic vs. open radical cystectomy for bladder cancer: Perioperative and pathologic results” Jeff Nix, Angela Smith, Raj Kurpad, Matthew E. Nielsen, Eric M. Wallen, Raj S. Pruthi, Division of Urologic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC

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Eur Uroljavascript:AL_get(this, ‘jour’, ‘Eur Urol.’); 2010;57:196–201 (Epub 2009 Oct 20) Eur Urol 2010;57:202–3; author reply 203–4 http://www.ncbi.nlm.nih.gov/pubmed/19931975?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract (Source: Urologic Oncology: Seminars and Original Investigations) Source: MedWorm: Bladder Cancer

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Beyond the Abstract – MicroRNA-125b suppresses the development of bladder … – UroToday

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Beyond the Abstract – MicroRNA-125b suppresses the development of bladder
UroToday
BERKELEY, CA (UroToday.com) – Urinary bladder cancer is the most common urological tumor in China 1 and is the fifth most common malignancy worldwide;

Source: bladder cancer – Google News

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Comparison of the new American Joint Committee on Cancer substratification in node‐negative pT2 urothelial carcinoma of the bladder: analysis of patient outcomes in a contemporary series

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Study Type – Prognosis (case series)
Level of Evidence 4 (Source: BJU International)

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Source: MedWorm: Bladder Cancer

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β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation

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β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation

Oncogene advance online publication, September 6, 2010. doi:10.1038/onc.2010.399

Authors: I Ahmad, J P Morton, L B Singh, S M Radulescu, R A Ridgway, S Patel, J Woodgett, D J Winton, M M Taketo, X-R Wu, H Y Leung
& O J Sansom (Source: Oncogene) Source: MedWorm: Bladder Cancer

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New Developments in Bladder Cancer Diagnosis – PR Web (press release)

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New Developments in Bladder Cancer Diagnosis
PR Web (press release)
According to the American Cancer Society, approximately 70530 new cases of bladder cancer will be diagnosed this year, resulting in nearly 15000 deaths.

Source: bladder cancer – Google News

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Development of Bladder Outlet Obstruction After a Single Treatment of Prostate Cancer with High-Intensity Focused Ultrasound: Experience with 226 Patients

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Journal of Endourology , Vol. 0, No. 0. (Source: Journal of Endourology) Source: MedWorm: Bladder Cancer

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Clinical Value of Fluorine-18 2-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography/Computed Tomography in Bladder Cancer [Phase I and Clinical Pharmacology]

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Conclusion
FDG-PET/CT has excellent sensitivity and specificity in the detection of metastatic bladder cancer and provides additional diagnostic information that enhances clinical management more than CT/MRI alone. FDG-PET/CT scans may provide better accuracy in clinical information for directing therapy. (Source: Journal of Clinical Oncology) Source: MedWorm: Bladder Cancer

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Novel bladder preservation therapy for locally invasive bladder cancer: Combined therapy using balloon-occluded arterial infusion of anticancer agent and hemodialysis with concurrent radiation.

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Authors: Azuma H, Inamoto T, Ibuki N, Ubai T, Kotake Y, Takahara K, Kiyama S, Nomi H, Uehara H, Komura K, Yamamoto K, Narumi Y, Katsuoka Y
We investigated the effect of balloon-occluded arterial infusion (BOAI) of anticancer agent (cisplatin/gemcitabine), used concomitantly with hemodialysis, which delivers an extremely high concentration of anticancer agent to the site of a tumor without systemic adverse effects, along with concurrent radiation (referred to as the OMC-regimen) in patients with advanced bladder cancer. One hundred and ninety-two patients were assigned to receive either the OMC-regimen (n=96) or total cystectomy (n=96). Patients in the OMC-regimen group who failed to achieve CR underwent cystectomy, or secondary BOAI with an increased amount of CDDP or gemcitabine (1600…

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Source: MedWorm: Bladder Cancer

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